- Medical Sciences Building 3005 H
- Office 513-558-3870
- Email desaipb@ucmail.uc.edu
Pharmacokinetics and pharmacodynamics of anticancer drugs, inter-individual and inter-species variation in drug metabolism, drug delivery systems
Peer Reviewed Publications
Illamola, Sílvia M; Bhongsatiern, Jiraganya Jj; Birnbaum, Angela K; Kumar, Shaun S; Courter, Joshua D; Haslam, David B; Allegaert, Karel; Reith, David M; Desai, Pankaj B; Sherwin, Catherine M 2025. Vancomycin dosing in neonates: enhancing outcomes using population pharmacokinetics and simulation. Frontiers in antibiotics, 4 , 1568931
Mersich, Ian; Congrove, Sunny; Horchar, Matthew; Caceres, Roman; Muraleedharan, Ranjithmenon; Desai, Janki; Desai, Pankaj; Sallans, Larry; Reisz, Julie A; Grier, Abby; Hass, Matthew R; Donmez, Omer; Yin, Cailing; Weirauch, Matthew T; Kottyan, Leah; Stevenson, Charles B; Sun, Claire; de Blank, Peter; Pillay-Smiley, Natasha; Hummel, Trent R; Elumalai, Nagarajan; Tavassoli, Ali; Firestein, Ron; Phoenix, Timothy N; D'Alessandro, Angelo; Dasgupta, Biplab 2025. Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG. bioRxiv : the preprint server for biology, ,
Bhattacharya, Debanjan; Barrile, Riccardo; Toukam, Donatien Kamdem; Gawali, Vaibhavkumar S; Kallay, Laura; Ahmed, Taukir; Brown, Hawley; Rezvanian, Sepideh; Karve, Aniruddha; Desai, Pankaj B; Medvedovic, Mario; Wang, Kyle; Ionascu, Dan; Harun, Nusrat; Vallabhapurapu, Subrahmanya; Wang, Chenran; Qi, Xiaoyang; Baschnagel, Andrew M; Kritzer, Joshua A; Cook, James M; Pomeranz Krummel, Daniel A; Sengupta, Soma 2024. GABA(A) Receptor Activation Drives GABARAP-Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors. Cancers, 16 18,
Desai, Pankaj B; Karve, Aniruddha S; Zawit, Misam; Arora, Priyanka; Dave, Nimita; Awosika, Joy; Li, Ningjing; Fuhrman, Bethany; Medvedovic, Mario; Sallans, Larry; Kendler, Ady; DasGupta, Biplab; Plas, David; Curry, Richard; Zuccarello, Mario; Chaudhary, Rekha; Sengupta, Soma; Wise-Draper, Trisha M 2024. A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research, 30 10, 2068-2077
Harlan, Sarah Schuman; Philpott, Carolyn D; Keegan, Shaun P; Droege, Molly E; Karve, Aniruddha S; Foreman, Brandon; Wakefield, Devin; Mueller, Eric W; Sangha, Kiranpal; Ngwenya, Laura B; Courter, Joshua D; Desai, Pankaj; Droege, Christopher 2024. Pharmacokinetics of Levetiracetam Seizure Prophylaxis in Severe Traumatic Brain Injury. The Annals of pharmacotherapy, 58 7, 705-714
Karve, Aniruddha S; Desai, Janki M; Gadgil, Sidharth N; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Yogendran, Lalanthica; Sengupta, Soma; Plas, David R; Desai, Pankaj B 2024. A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance. International journal of molecular sciences, 25 6,
Oatman, Nicole; Gawali, Mruniya V; Congrove, Sunny; Cáceres, Román; Sukumaran, Abitha; Gupta, Nishtha; Murugesan, Narmadha; Arora, Priyanka; Subramanian, Srividhya; Choi, Kwangmin; Abdel-Malek, Zalfa; Reisz, Julie A; Stephenson, Daniel; Amaravadi, Ravi; Desai, Pankaj; D'Alessandro, Angelo; Komurov, Kakajan; Dasgupta, Biplab 2024. A Multimodal Drug-Diet-Immunotherapy Combination Restrains Melanoma Progression and Metastasis. Cancer research, 84 14, 2333-2351
Bhattacharya, Debanjan; Barille, Riccardo; Toukam, Donatien Kamdem; Gawali, Vaibhavkumar S; Kallay, Laura; Ahmed, Taukir; Brown, Hawley; Rezvanian, Sepideh; Karve, Aniruddha; Desai, Pankaj B; Medvedovic, Mario; Wang, Kyle; Ionascu, Dan; Harun, Nusrat; Wang, Chenran; Baschnagel, Andrew M; Kritzer, Joshua A; Cook, James M; Pomeranz Krummel, Daniel A; Sengupta, Soma 2023. GABA(A) receptor activation drives GABARAP-Nix mediated autophagy to radiation-sensitize primary and brain-metastatic lung adenocarcinoma tumors. bioRxiv : the preprint server for biology, ,
Desai, Janki M; Karve, Aniruddha S; Gudelsky, Gary A; Gawali, Mruniya V; Seibel, William; Sallans, Larry; DasGupta, Biplab; Desai, Pankaj B 2022. Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma. Investigational new drugs, 40 5, 944-952
Karve, Aniruddha S; Desai, Janki M; Dave, Nimita; Wise-Draper, Trisha M; Gudelsky, Gary A; Phoenix, Timothy N; DasGupta, Biplab; Sengupta, Soma; Plas, David R; Desai, Pankaj B 2022. Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. Cancer chemotherapy and pharmacology, 90 4, 345-356
Arora, Priyanka; Gudelsky, Gary; Desai, Pankaj B 2021. Gender-based differences in brain and plasma pharmacokinetics of letrozole in sprague-dawley rats: Application of physiologically-based pharmacokinetic modeling to gain quantitative insights. PloS one, 16 4, e0248579
Koehler, Abigail; Karve, Aniruddha; Desai, Pankaj; Arbiser, Jack; Plas, David R; Qi, Xiaoyang; Read, Renee D; Sasaki, Atsuo T; Gawali, Vaibhavkumar S; Toukam, Donatien K; Bhattacharya, Debanjan; Kallay, Laura; Pomeranz Krummel, Daniel A; Sengupta, Soma 2021. Reuse of Molecules for Glioblastoma Therapy. Pharmaceuticals (Basel, Switzerland), 14 2,
Mishra, Rosalin; Yuan, Long; Patel, Hima; Karve, Aniruddha S; Zhu, Haizhou; White, Aaron; Alanazi, Samar; Desai, Pankaj; Merino, Edward J; Garrett, Joan T 2021. Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth. International journal of molecular sciences, 22 4,
Oatman, Nicole; Dasgupta, Nupur; Arora, Priyanka; Choi, Kwangmin; Gawali, Mruniya V; Gupta, Nishtha; Parameswaran, Sreeja; Salomone, Joseph; Reisz, Julie A; Lawler, Sean; Furnari, Frank; Brennan, Cameron; Wu, Jianqiang; Sallans, Larry; Gudelsky, Gary; Desai, Pankaj; Gebelein, Brian; Weirauch, Matthew T; D'Alessandro, Angelo; Komurov, Kakajan; Dasgupta, Biplab 2021. Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer. Science advances, 7 7,
Davis, Harold W; Vallabhapurapu, Subrahmanya D; Chu, Zhengtao; Wyder, Michael A; Greis, Kenneth D; Fannin, Venette; Sun, Ying; Desai, Pankaj B; Pak, Koon Y; Gray, Brian D; Qi, Xiaoyang 2020. Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles. Cells, 9 9,
Gulati, Shuchi; Desai, Janki; Palackdharry, Sarah M; Morris, John C; Zhu, Zheng; Jandarov, Roman; Riaz, Muhammad K; Takiar, Vinita; Mierzwa, Michelle; Gutkind, J Silvio; Molinolo, Alfredo; Desai, Pankaj B; Sadraei, Nooshin Hashemi; Wise-Draper, Trisha M 2020. Phase 1 dose-finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer. Cancer, 126 2, 354-362
Arora, Priyanka; Adams, Courtney Huff; Gudelsky, Gary; DasGupta, Biplab; Desai, Pankaj B 2019. Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats. Cancer chemotherapy and pharmacology, 83 1, 81-89
Ananthula, Hari Krishna; Parker, Scott; Touchette, Erin; Buller, R Mark; Patel, Gopi; Kalman, Daniel; Salzer, Johanna S; Gallardo-Romero, Nadia; Olson, Victoria; Damon, Inger K; Moir-Savitz, Tessa; Sallans, Larry; Werner, Milton H; Sherwin, Catherine M; Desai, Pankaj B 2018. Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents. BMC pharmacology & toxicology, 19 1, 80
Lazzarini, Cristina; Haranahalli, Krupanandan; Rieger, Robert; Ananthula, Hari Krishna; Desai, Pankaj B; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie T; Ruzsicska, Bela; Haley, John; Ojima, Iwao; Del Poeta, Maurizio 2018. Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids. Antimicrobial agents and chemotherapy, 62 5,
Mehta, Rajiv; Kabrawala, Mayank; Nandwani, Subhash; Desai, Pankaj; Bhayani, Vishwa; Patel, Sanjay; Parekh, Viral 2018. Safety and Efficacy of Sofosbuvir and Daclatasvir for Hepatitis C Virus Infection in Patients with β-Thalassemia Major. Journal of clinical and experimental hepatology, 8 1, 3-6
Mor, Visesato; Rella, Antonella; Farnoud, Amir M; Singh, Ashutosh; Munshi, Mansa; Bryan, Arielle; Naseem, Shamoon; Konopka, James B; Ojima, Iwao; Bullesbach, Erika; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie; Collins, Margaret; Ananthula, Hari Krishna; Sallans, Larry; Desai, Pankaj B; Wiederhold, Nathan P; Fothergill, Annette W; Kirkpatrick, William R; Patterson, Thomas; Wong, Lai Hong; Sinha, Sunita; Giaever, Guri; Nislow, Corey; Flaherty, Patrick; Pan, Xuewen; Cesar, Gabriele Vargas; de Melo Tavares, Patricia; Frases, Susana; Miranda, Kildare; Rodrigues, Marcio L; Luberto, Chiara; Nimrichter, Leonardo; Del Poeta, Maurizio 2018. Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids". mBio, 9 2,
Wise-Draper, Trisha M; Moorthy, Ganesh; Salkeni, Mohamad A; Karim, Nagla Abdel; Thomas, Hala Elnakat; Mercer, Carol A; Beg, M Shalaan; O'Gara, Sue; Olowokure, Olugbenga; Fathallah, Hassana; Kozma, Sara C; Thomas, George; Rixe, Olivier; Desai, Pankaj; Morris, John C 2017. A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies. Targeted oncology, 12 3, 323-332
Bhongsatiern, Jiraganya; Stockmann, Chris; Yu, Tian; Constance, Jonathan E; Moorthy, Ganesh; Spigarelli, Michael G; Desai, Pankaj B; Sherwin, Catherine M T 2016. Renal Function Descriptors in Neonates: Which Creatinine-Based Formula Best Describes Vancomycin Clearance? Journal of clinical pharmacology, 56 5, 528-40
Bhongsatiern, Jiraganya; Stockmann, Chris; Roberts, Jessica K; Yu, Tian; Korgenski, Kent E; Spigarelli, Michael G; Desai, Pankaj B; Sherwin, Catherine M T 2015. Evaluation of Vancomycin Use in Late-Onset Neonatal Sepsis Using the Area Under the Concentration-Time Curve to the Minimum Inhibitory Concentration ≥400 Target. Therapeutic drug monitoring, 37 6, 756-65
Dave, Nimita; Chow, Lionel M L; Gudelsky, Gary A; LaSance, Kathleen; Qi, Xiaoyang; Desai, Pankaj B 2015. Preclinical pharmacological evaluation of letrozole as a novel treatment for gliomas. Molecular cancer therapeutics, 14 4, 857-64
Moorthy, Ganesh; Sallee, Floyd; Gabbita, Prasad; Zemlan, Frank; Sallans, Larry; Desai, Pankaj B 2015. Safety, tolerability and pharmacokinetics of 2-pyridylacetic acid, a major metabolite of betahistine, in a phase 1 dose escalation study in subjects with ADHD. Biopharmaceutics & drug disposition, 36 7, 429-39
Mor, Visesato; Rella, Antonella; Farnoud, Amir M; Singh, Ashutosh; Munshi, Mansa; Bryan, Arielle; Naseem, Shamoon; Konopka, James B; Ojima, Iwao; Bullesbach, Erika; Ashbaugh, Alan; Linke, Michael J; Cushion, Melanie; Collins, Margaret; Ananthula, Hari Krishna; Sallans, Larry; Desai, Pankaj B; Wiederhold, Nathan P; Fothergill, Annette W; Kirkpatrick, William R; Patterson, Thomas; Wong, Lai Hong; Sinha, Sunita; Giaever, Guri; Nislow, Corey; Flaherty, Patrick; Pan, Xuewen; Cesar, Gabriele Vargas; de Melo Tavares, Patricia; Frases, Susana; Miranda, Kildare; Rodrigues, Marcio L; Luberto, Chiara; Nimrichter, Leonardo; Del Poeta, Maurizio 2015. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. mBio, 6 3, e00647
Krishan, Mansi; Gudelsky, Gary A; Desai, Pankaj B; Genter, Mary Beth 2014. Manipulation of olfactory tight junctions using papaverine to enhance intranasal delivery of gemcitabine to the brain. Drug delivery, 21 1, 8-16
Dave, Nimita; Gudelsky, Gary A; Desai, Pankaj B 2013. The pharmacokinetics of letrozole in brain and brain tumor in rats with orthotopically implanted C6 glioma, assessed using intracerebral microdialysis. Cancer chemotherapy and pharmacology, 72 2, 349-57
Mu, Chaofeng; Dave, Nimita; Hu, Jing; Desai, Pankaj; Pauletti, Giovanni; Bai, Shuhua; Hao, Jiukuan 2013. Solubilization of flurbiprofen into aptamer-modified PEG-PLA micelles for targeted delivery to brain-derived endothelial cells in vitro. Journal of microencapsulation, 30 7, 701-8
Tong, Jenny; Dave, Nimita; Mugundu, Ganesh M; Davis, Harold W; Gaylinn, Bruce D; Thorner, Michael O; Tschöp, Matthias H; D'Alessio, David; Desai, Pankaj B 2013. The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects. European journal of endocrinology, 168 6, 821-8
Liu, Li; Mugundu, Ganesh M; Kirby, Brian J; Samineni, Divya; Desai, Pankaj B; Unadkat, Jashvant D 2012. Quantification of human hepatocyte cytochrome P450 enzymes and transporters induced by HIV protease inhibitors using newly validated LC-MS/MS cocktail assays and RT-PCR. Biopharmaceutics & drug disposition, 33 4, 207-17
Mugundu, Ganesh M; Sallans, Larry; Guo, Yingying; Shaughnessy, Elizabeth A; Desai, Pankaj B 2012. Assessment of the impact of CYP3A polymorphisms on the formation of α-hydroxytamoxifen and N-desmethyltamoxifen in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 40 2, 389-96
Samineni, Divya; Desai, Pankaj B; Sallans, Larry; Fichtenbaum, Carl J 2012. Steady-state pharmacokinetic interactions of darunavir/ritonavir with lipid-lowering agent rosuvastatin. Journal of clinical pharmacology, 52 6, 922-31
He, Bing; Tang, Jie; Ding, Ying; Wang, Huijun; Sun, Yuyin; Shin, Jae Hong; Chen, Bin; Moorthy, Ganesh; Qiu, Judy; Desai, Pankaj; Wild, David J 2011. Mining relational paths in integrated biomedical data. PloS one, 6 12, e27506
Jackson, Richard L; Greiwe, Jeffrey S; Desai, Pankaj B; Schwen, Richard J 2011. Single-dose and steady-state pharmacokinetic studies of S-equol, a potent nonhormonal, estrogen receptor β-agonist being developed for the treatment of menopausal symptoms. Menopause (New York, N.Y.), 18 2, 185-93
Kirby, Brian J; Collier, Ann C; Kharasch, Evan D; Dixit, Vaishali; Desai, Pankaj; Whittington, Dale; Thummel, Kenneth E; Unadkat, Jashvant D 2011. Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. Drug metabolism and disposition: the biological fate of chemicals, 39 12, 2329-37
Mugundu, Ganesh M; Hariparsad, Niresh; Desai, Pankaj B 2010. Impact of ritonavir, atazanavir and their combination on the CYP3A4 induction potential of efavirenz in primary human hepatocytes. Drug metabolism letters, 4 1, 45-50
Apparaju, Sandhya Kiran; Gudelsky, Gary A; Desai, Pankaj B 2008. Pharmacokinetics of gemcitabine in tumor and non-tumor extracellular fluid of brain: an in vivo assessment in rats employing intracerebral microdialysis. Cancer chemotherapy and pharmacology, 61 2, 223-9
Gupta, Anshul; Mugundu, Ganesh M; Desai, Pankaj B; Thummel, Kenneth E; Unadkat, Jashvant D 2008. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 36 6, 1172-80
Sane, Rucha S; Buckley, Donna J; Buckley, Arthur R; Nallani, Srikanth C; Desai, Pankaj B 2008. Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells. Drug metabolism and disposition: the biological fate of chemicals, 36 5, 946-54
Dixit, Vaishali; Hariparsad, Niresh; Desai, Pankaj; Unadkat, Jashvant D 2007. In vitro LC-MS cocktail assays to simultaneously determine human cytochrome P450 activities. Biopharmaceutics & drug disposition, 28 5, 257-62
Dixit, Vaishali; Hariparsad, Niresh; Li, Fang; Desai, Pankaj; Thummel, Kenneth E; Unadkat, Jashvant D 2007. Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. Drug metabolism and disposition: the biological fate of chemicals, 35 10, 1853-9
Al-Zoughool, Mustafa; Succop, Paul; Desai, Pankaj; Vietas, Jay; Talaska, Glenn 2006. Effect of N-glucuronidation on urinary bladder genotoxicity of 4-aminobiphenyl in male and female mice. Environmental toxicology and pharmacology, 22 2, 153-9
Desai, Pankaj B; Sane, Rucha S 2006. Metabolism and Pharmacokinetics of Anti-Cancer Drugs. Toxicology in vitro : an international journal published in association with BIBRA, 20 2, 133-4
Kelly, Burnett; Melhem, Murad; Zhang, Jianhua; Kasting, Gerald; Li, Jinsong; Krishnamoorthy, Mahesh; Heffelfinger, Sue; Rudich, Steven; Desai, Pankaj; Roy-Chaudhury, Prabir 2006. Perivascular paclitaxel wraps block arteriovenous graft stenosis in a pig model. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 21 9, 2425-31
Melhem, Murad; Kelly, Burnett; Zhang, Jianhua; Kasting, Gerald; Li, Jinsong; Davis, Harold; Heffelfinger, Sue; Desai, Pankaj; Roy-Chaudhury, Prabir 2006. Development of a local perivascular paclitaxel delivery system for hemodialysis vascular access dysfunction: polymer preparation and in vitro activity. Blood purification, 24 3, 289-98
Winhusen, Theresa; Somoza, Eugene; Singal, Bonita M; Harrer, Judy; Apparaju, Sandhya; Mezinskis, Juris; Desai, Pankaj; Elkashef, Ahmed; Chiang, C Nora; Horn, Paul 2006. Methylphenidate and cocaine: a placebo-controlled drug interaction study. Pharmacology, biochemistry, and behavior, 85 1, 29-38
Roy-Chaudhury, Prabir; Kelly, Burnett S; Melhem, Murad; Zhang, Jianhua; Li, Jinsong; Desai, Pankaj; Munda, Rino; Heffelfinger, Sue C 2005. Vascular access in hemodialysis: issues, management, and emerging concepts. Cardiology clinics, 23 3, 249-73
Roy-Chaudhury, Prabir; Kelly, Burnett S; Melhem, Murad; Zhang, Jianhua; Li, Jinsong; Desai, Pankaj; Munda, Rino; Heffelfinger, Sue C 2005. Novel therapies for hemodialysis vascular access dysfunction: fact or fiction! Blood purification, 23 1, 29-35
Setchell, Kenneth D R; Brzezinski, Amnon; Brown, Nadine M; Desai, Pankaj B; Melhem, Murad; Meredith, Trevor; Zimmer-Nechimias, Linda; Wolfe, Brian; Cohen, Yoram; Blatt, Yoav 2005. Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women. Journal of agricultural and food chemistry, 53 6, 1938-44
Einhaus, Charity M; Retzinger, Andrew C; Perrotta, Andre O; Dentler, Michael D; Jakate, Abhijeet S; Desai, Pankaj B; Retzinger, Gregory S 2004. Fibrinogen-coated droplets of olive oil for delivery of docetaxel to a fibrin(ogen)-rich ascites form of a murine mammary tumor. Clinical cancer research : an official journal of the American Association for Cancer Research, 10 20, 7001-10
Hariparsad, Niresh; Nallani, Srikanth C; Sane, Rucha S; Buckley, Donna J; Buckley, Arthur R; Desai, Pankaj B 2004. Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital. Journal of clinical pharmacology, 44 11, 1273-81
Nallani, Srikanth C; Goodwin, Bryan; Buckley, Arthur R; Buckley, Donna J; Desai, Pankaj B 2004. Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes. Cancer chemotherapy and pharmacology, 54 3, 219-29
Jakate, Abhijeet S; Einhaus, Charity M; DeAnglis, Ashley P; Retzinger, Gregory S; Desai, Pankaj B 2003. Preparation, characterization, and preliminary application of fibrinogen-coated olive oil droplets for the targeted delivery of docetaxel to solid malignancies. Cancer research, 63 21, 7314-20
Nallani, Srikanth C; Glauser, Tracy A; Hariparsad, Niresh; Setchell, Kenneth; Buckley, Donna J; Buckley, Arthur R; Desai, Pankaj B 2003. Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate. Epilepsia, 44 12, 1521-8
Nallani, Srikanth C; Goodwin, Bryan; Maglich, Jodi M; Buckley, Donna J; Buckley, Arthur R; Desai, Pankaj B 2003. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor. Drug metabolism and disposition: the biological fate of chemicals, 31 5, 681-4
Roy-Chaudhury, Prabir; Kelly, Burnett S; Zhang, Jianhua; Narayana, Ashwath; Desai, Pankaj; Melham, Murad; Duncan, Heather; Heffelfinger, Sue C 2003. Hemodialysis vascular access dysfunction: from pathophysiology to novel therapies. Blood purification, 21 1, 99-110
Setchell, Kenneth D R; Brown, Nadine Maynard; Desai, Pankaj B; Zimmer-Nechimias, Linda; Wolfe, Brian; Jakate, Abhijeet S; Creutzinger, Vivian; Heubi, James E 2003. Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes. The Journal of nutrition, 133 4, 1027-35
Desai, Pankaj B; Nallani, Srikanth C; Sane, Rucha S; Moore, Linda B; Goodwin, Bryan J; Buckley, Donna J; Buckley, Arthur R 2002. Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen. Drug metabolism and disposition: the biological fate of chemicals, 30 5, 608-12
Genter, Mary Beth; Apparaju, Sandhya; Desai, Pankaj B 2002. Induction of olfactory mucosal and liver metabolism of lidocaine by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Journal of biochemical and molecular toxicology, 16 3, 128-34
Roy-Chaudhury, Prabir; Kelly, Burnett S; Narayana, Ashwath; Desai, Pankaj; Melhem, Murad; Munda, Rino; Duncan, Heather; Heffelfinger, Sue C 2002. Hemodialysis vascular access dysfunction from basic biology to clinical intervention. Advances in renal replacement therapy, 9 2, 74-84
Stevens, Ruth E; Konsil, Julraht; Verrill, Sonya S; Roy, Partha; Desai, Pankaj B; Upmalis, David H; Cone, Frederick L 2002. Bioavailability study of a 1200 mg miconazole nitrate vaginal ovule in healthy female adults. Journal of clinical pharmacology, 42 1, 52-60